BDBM10866 4-amino-6-(trifluoromethyl)benzene-1,3-disulfonamide::CHEMBL418::aromatic/heteroaromatic sulfonamide 11
SMILES Nc1cc(c(cc1S(N)(=O)=O)S(N)(=O)=O)C(F)(F)F
InChI Key InChIKey=KRVABEGPNKGLOT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 10866
Affinity DataKi: 61nMAssay Description:Inhibition of recombinant Sulfurihydrogenibium yellowstonense YO3AOP1 carbonic anhydrase by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 223nMAssay Description:Inhibition of Saccharomyces cerevisiae recombinant CA expressed in Escherichia coli by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 367nMAssay Description:Inhibition of cloned Stylophora pistillata alpha-CA expressed in human HEK293 cells by stopped-flow CO2 assayMore data for this Ligand-Target Pair
Affinity DataKi: 367nMAssay Description:Inhibition of Stylophora pistillata carbonic anhydrase by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 402nMAssay Description:Inhibition of Helicobacter pylori recombinant CAMore data for this Ligand-Target Pair
Affinity DataKi: 481nMAssay Description:Inhibition of Stylophora pistillata carbonic anhydrase 2 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 552nMAssay Description:Inhibition of GST-tagged astrosclera willeyana Astrosclerin-3 expressed in Escherichia coli after 15 mins preincubation by stopped flow CO2 hydration...More data for this Ligand-Target Pair
Affinity DataKi: 830nMAssay Description:Inhibitory activity against alpha carbonic anhydrase (Zn-Cam) from Methanosarcina thermophilaMore data for this Ligand-Target Pair
Affinity DataKi: 950nMAssay Description:Inhibitory activity against alpha carbonic anhydrase (Co-Cam) from Methanosarcina thermophilaMore data for this Ligand-Target Pair
TargetCarbonic anhydrase(Cryptococcus neoformans var. grubii (Filobasidiell...)
Universite Degli Studi Di Firenze
Universite Degli Studi Di Firenze
Affinity DataKi: 968nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 2.35E+3nM ΔG°: -7.55kcal/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
TargetCarbonic anhydrase(Anopheles gambiae)
University Of Tampere And Tampere University Hospital
Curated by ChEMBL
University Of Tampere And Tampere University Hospital
Curated by ChEMBL
Affinity DataKi: 4.36E+3nMAssay Description:Inhibition of Anopheles gambiae carbonic anhydrase pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.12E+3nM ΔG°: -6.99kcal/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
TargetCarbonic anhydrase(Methanobacterium thermoautotrophicum)
Pennsylvania State University
Curated by ChEMBL
Pennsylvania State University
Curated by ChEMBL
Affinity DataKi: 5.00E+4nMAssay Description:Inhibitory activity against beta carbonic anhydrase (Cab) from Methanobacterium thermoautotrophicumMore data for this Ligand-Target Pair